DMPO

N° du produit ABIN1027923

Aperçu rapide pour DMPO (ABIN1027923)

Détail du produit

Fonction: Spin trapping reagent

Attributs du produit: Nitrone adduct formation.

Pureté: >98 %

Chemical Name: 2,2-Dimethyl-3,4-dihydro-2H-pyrrole 1-oxide, 5,5-Dimethyl-1-Pyrroline-N-Oxide, 3,​4-​dihydro-​2,​3-​dimethyl-​2H-​pyrrole 1-​oxide

Formula: C6H11NO

Solubility: Soluble to 100 mM in ethanol and to 100 mM in DMSO

Information d'application

Commentaires:

Source: Synthetic.
Appearance: Liquid

Restrictions: For Research Use only

Stockage

Format: Solid

Précaution d'utilisation: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes

Conseil sur la manipulation: Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes

Stock: -20 °C

Détail du antigène

Sujet: The formation of free radicals and other highly reactive oxygen species has been implicated in the pathogenesis of many disease states. The ability to identify these species is crucial, and spin trapping has accomplished this goal. DMPO (5,5-dimethyl-1-pyrroline N-oxide) is one of the least toxic to cells and animals, and possesses convenient pharmacokinetics (uptake, distribution, metabolism and excretion) in biological systems (2-6). Recent studies have determined that nitric oxide may substantially affect the quantitative determination of DMPO adducts, and therefore extra caution is required when studying generation of these species in the presence of nitric oxide or its radicals. DMPO adducts can be generated with protein and DNA radicals.

Poids moléculaire: 113.16

Numéro CAS: 3317-61-1